Researcher

Name

Shunsuke Kotani

Research field

Organic Chemistry

小谷 俊介

Research content

"Catalytic Asymmetric Synthesis Using Chiral Organic Molecules"

A number of materials such as amino acids, sugars and nucleosides constructing our body are chiral molecules. The chirality of bioactive substances used as a medicine has a great influence on bioactivity in our body. Therefore, synthesis of one of the stereoisomers possessing chirality is required.

"Catalytic enantioselelctive synthesis" can theoretically allows to produce a large quantity of one optically pure isomer using a small amount of a chiral catalyst. Therefore, the design of small organic catalysts is a key for the development of enantioselective reaction. Moreover, organocatalysis is a subject of great interest in the field of synthetic chemistry, because of its environmentally benign nature. They don't need any precious or toxic metallic compounds as catalysts.

My group aims to develop novel methodologies of organic synthesis by using small organic molecules as a catalyst. Development of new methods and strategies for synthesis of biologically active compounds is also involved.

Career

  • 1999-2003 Bachelor course, Department of Pharmaceutical Sciences, Hokkaido University
  • 2003-2005 2003-2005 Master course, Graduate School of Pharmaceutical Sciences, Hokkaido University
  • 2005-2008 Ph.D. course, Graduate School of Pharmaceutical Sciences, Kumamoto University
  • 2008-2009 Postdoctoral fellow, University of California, Irvine (Supervisor: Prof. Scott, D. Rychnovsky)
  • 2007-2009 Research Fellow of the Japan Society for the Promotion of Science
  • 2009-2014 Assistant Professor, Priority Organization for Innovation and Excellence, Kumamoto University
  • 2014- Associate Professor, Priority Organization for Innovation and Excellence, Kumamoto University
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